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Fertility Treatments

1. IUI (H) – Intrauterine Insemination with Husband’s Sperm

Definition: IUI (H) is a fertility treatment in which a processed sample of the husband’s sperm is placed directly into the woman’s uterus around the time of ovulation.

Process:

  • Ovulation is monitored (with or without fertility medications).
  • Semen sample is collected from the husband.
  • The sperm is “washed” (to separate healthy, motile sperm).
  • Using a thin catheter, sperm is placed inside the uterus.

When Used:

  • Unexplained infertility.
  • Mild male factor infertility (low sperm count or motility).
  • Cervical factor infertility.

Advantages: Simple, less invasive, and affordable compared to IVF.

2. IUI (D) – Intrauterine Insemination with Donor Sperm

Definition: IUI (D) is the same procedure as IUI (H), but it uses donor sperm instead of the husband’s.

Process:

  • Donor sperm is selected (from a certified sperm bank).
  • The sperm sample is thawed, processed, and placed inside the woman’s uterus during ovulation.

When Used:

  • Severe male infertility (no sperm or very poor quality).
  • Genetic disorders in the male partner.
  • Single women or same-sex couples wanting pregnancy.

Advantages: Provides a chance of pregnancy when the partner’s sperm is not suitable.

3. IVF – In Vitro Fertilization

Definition: IVF is a process where eggs are collected from the woman’s ovaries and fertilized with sperm outside the body in a laboratory. The resulting embryo is then transferred into the uterus.

Process:

  • Ovarian stimulation with fertility drugs.
  • Egg retrieval (minor surgical procedure).
  • Sperm collection and preparation.
  • Fertilization in the lab (egg + sperm in a dish).
  • Embryo culture for a few days.
  • Embryo transfer into the uterus.

When Used:

  • Fallopian tube blockage/damage.
  • Endometriosis.
  • Severe male infertility.
  • Failed IUI cycles.
  • Unexplained infertility.

Advantages: Higher success rates than IUI; possibility of freezing embryos for future use.

4. ICSI – Intracytoplasmic Sperm Injection

Definition: ICSI is an advanced IVF technique where a single healthy sperm is directly injected into an egg under a microscope.

Process:

  • Eggs are retrieved from the woman (as in IVF).
  • A single sperm is selected and injected into each egg using a microneedle.
  • The fertilized embryo is cultured and later transferred to the uterus.

When Used:

  • Severe male infertility (very low sperm count, poor motility, or abnormal sperm).
  • Previous IVF failure (poor fertilization).
  • Use of frozen sperm or surgically retrieved sperm (TESE, PESA).

Advantages: Overcomes almost all male infertility problems; gives higher chances of fertilization.

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